For centers that are enrolled in Nightingale Time Series reporting you will either get a message in eNICQ 6 to turn on the PHI submissions or be asked to enable it by a support tech.
To enable PHI submissions you just need to log into eNICQ 6 and click on the Advanced Menu Options (the gear icon in the top right). When that menu opens select Center Management:
Then click the appropriate center so it's highlighted in blue and click the "Set PHI Submission" button at the bottom:
Finally, on the next screen click the "Enable PHI Submission" button: